Collagen (Collasel TRIPEPTIDE®)

Collagen is the most abundant protein in the human body. It forms the structural framework for our skin, joints, bones, muscles, and gut lining. Think of it as the body’s internal scaffolding - providing strength, elasticity, and stability to connective tissues.

Our formula uses CollaSel TRIPEPTIDE®, an advanced form of collagen that has been enzymatically broken down into highly bioavailable tripeptides. These smaller peptides (500 dalton) are designed to be efficiently absorbed and utilised by the body.

By delivering collagen in a highly targeted form, CollaSel TRIPEPTIDE® supports the body’s natural structural network.

What Collagen (Collasel TRIPEPTIDE®) can do for you?

Skin: Clinically shown to increase collagen synthesis in skin, hair, nails and connective tissues.

Joints:  Helps maintain strength, mobility and post-exercise recovery. 

Gut: Provides gentle support to strengthen the gut lining and overall digestive health. 

Healthy ageing: Helps maintain cell wall integrity and soft tissues that naturally decline with age because of reduced collagen production.

The Science

From our mid-20s, natural collagen production begins to decline by around 1% each year. This gradual reduction affects many areas of the body, leading to:

Reduced skin elasticity 
Slower recovery after exercise 
Stiffness in joints 
Weakening of hair and nails 
Increased gut sensitivity

According to the American Academy of Dermatology, women lose 30% of their skin’s collagen in the five years following menopause. 

Collagen provides the following:

Support for the body’s natural collagen-building pathways
Helps maintain skin elasticity, hydration and firmness
Support for joints, ligaments and mobility
Gentle support for gut lining integrity
Support for hair and nail strength
Support for healthy ageing and recovery

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Products with Collagen (Collasel TRIPEPTIDE®)

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The Naked Pharmacy

Naked Collagen - Hydrolysed Bovine Collagen

From£33.75

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The Studies

At The Naked Pharmacy, we ensure that all of our supplements are made with effective strength bioactives, so they are clinically proven to work.

We aim for each supplement to be scientifically supported by multiple randomised placebo-controlled studies. All clinical trial studies we use to support our supplements are undertaken on human patients, using the same dosage and formulation of the product. The scientific studies are published in peer review journals.

Study: Anti-Aging Effects of Low-Molecular-Weight Collagen Peptide Supplementation on Facial Wrinkles and Skin Hydration: Outcomes from a Six-Week Randomised, Double-Blind, Placebo-Controlled Trial 

What was the study about:

Using validated objective methods, participants were provided with low-molecular weight collagen, to see its effects on skin ageing and health.

How was the study conducted:

The trial was conducted with 80 healthy women aged 30 years and older. They received a daily oral dose of either the food supplement or placebo for six weeks.

What did the study find?

After 6 weeks, Tripeptide Collagen consumption had significant improvements in wrinkles with a reduction in volume by 46%, in area by 44%, and in depth by 9%, along with a greater increase in skin moisturisation (by 34%) than those in the placebo group.

Study: Analgesic efficacy of collagen peptide in knee osteoarthritis. Lin CR et al., 2023. Randomised, double-blind, placebo-controlled trial, 180 human participants with knee osteoarthritis.

What was the study about:

This study aims to evaluate the analgesic (pain relief) effects and safety of collagen peptide in patients diagnosed with knee osteoarthritis.

How was the study conducted:

A review of systematic literatures was conducted using multiple databases including PubMed, Scopus, EMBASE, Web of Science, Cochrane, and ClinicalTrials.gov.

Papers searched for randomised controlled trials (RCTs) published up to 27 May 2023 that focused on the pain relieving outcomes and adverse events associated with collagen peptides or hydrolysed collagen in patients with osteoarthritis.

What did the study find?

Findings demonstrate significant pain relief in patients with knee osteoarthritis who received collagen peptides compared to  those who received placebo.

Glossary of terms:

There are a few key terms to be aware of when reviewing these studies:

Randomised Clinical Trial

A clinical trial in which the participants are assigned randomly (by chance alone) to different treatments.

Double-blind study

A study in which neither the participants nor the experimenters know who is receiving a particular treatment. This procedure is utilised to prevent bias in research results.

Double-blind studies are particularly useful for preventing bias due to demand characteristics or the placebo effect.

P-value

The probability of obtaining the observed results of a test. The lower the p-value is, the more confident we can be of a true result. For example, a p- value of 0.001 confirms a result as 99.9% accurate.

Placebo

An inactive treatment used in a clinical trial, sometimes referred to as a “sugar pill”.

A placebo-controlled trial compares a new treatment with a placebo, in order to give greater confidence that the result is only due to the test/active ingredient.