Journal

Saffron — How it Works



Saffron has got to be one of the most versatile spices out there. Not only is it used as a fabric dye, an ingredient in perfume and in a variety of delicious dishes from all over the world, it also has a long rich history of being used in traditional medicine.

We can trace back saffron’s use in treatment as far as the Sumerian civilisation during the Early Bronze ages and it’s been part of traditional practice ever since.

We’re all about plant power here at The Naked Pharmacy, which is why we’re harnessing the exciting qualities of saffron in our products too. Read on to learn more about the many benefits of this vibrant spice.

So what’s in saffron?



Saffron has multiple micronutrients and flavonoid bioactives (antioxidants) within its flower. The primary bioactives are Safranal, Crocin, and Picrocrocin. These compounds benefit different bodily systems in multiple ways. For example, Research shows that saffron actives work on serotonin production in the gut, where 90% of the happy hormone is produced.

How else are these Compounds working?

We know that saffron compounds are having an effect on the synapses and we also believe that most of the effect is happening in the gut, rather than the brain. Because of the gut-brain axis and the nerve connection between them, serotonin production in the gut can have an impact on mental health issues, such as nervousness, mood balance and sleep quality — basically all of the things that keep your mental health stable.

It’s also believed that saffron has an effect on other hormone levels that are produced in the gut too, for example, early morning cortisol levels. Saffron bioactives have neuroprotective effects, so they have an anti-inflammatory impact on the nerve connection between the gut and brain too.

Spoiler alert: your gut health is very important!



Research now shows that a variety of mental health conditions are affected by the health of the gut and not the central nervous system.

Saffron helps reduce the reactivity of the nervous system to stress by helping the body to cope better, sleep better and react better to nervousness and mood imbalance.

We’re certain saffron will continue to have a positive reputation in health going forward, as it has for the last few thousand years.

Sold on saffron? Our Saffrosun supplement is made with the exact effective strength of bioactives proven to work in clinical trials. Each batch is tested so that we can guarantee strength and quality of our ingredients.

We will update this post as further research is published, so stay tuned.



Saffron has got to be one of the most versatile spices out there. Not only is it used as a fabric dye, an ingredient in perfume and in a variety of delicious dishes from all over the world, it also has a long rich history of being used in traditional medicine.

We can trace back saffron’s use in treatment as far as the Sumerian civilisation during the Early Bronze ages and it’s been part of traditional practice ever since.

We’re all about plant power here at The Naked Pharmacy, which is why we’re harnessing the exciting qualities of saffron in our products too. Read on to learn more about the many benefits of this vibrant spice.

So what’s in saffron?



Saffron has multiple micronutrients and flavonoid bioactives (antioxidants) within its flower. The primary bioactives are Safranal, Crocin, and Picrocrocin. These compounds benefit different bodily systems in multiple ways. For example, Research shows that saffron actives work on serotonin production in the gut, where 90% of the happy hormone is produced.

How else are these Compounds working?

We know that saffron compounds are having an effect on the synapses and we also believe that most of the effect is happening in the gut, rather than the brain. Because of the gut-brain axis and the nerve connection between them, serotonin production in the gut can have an impact on mental health issues, such as nervousness, mood balance and sleep quality — basically all of the things that keep your mental health stable.

It’s also believed that saffron has an effect on other hormone levels that are produced in the gut too, for example, early morning cortisol levels. Saffron bioactives have neuroprotective effects, so they have an anti-inflammatory impact on the nerve connection between the gut and brain too.

Spoiler alert: your gut health is very important!



Research now shows that a variety of mental health conditions are affected by the health of the gut and not the central nervous system.

Saffron helps reduce the reactivity of the nervous system to stress by helping the body to cope better, sleep better and react better to nervousness and mood imbalance.

We’re certain saffron will continue to have a positive reputation in health going forward, as it has for the last few thousand years.

Sold on saffron? Our Saffrosun supplement is made with the exact effective strength of bioactives proven to work in clinical trials. Each batch is tested so that we can guarantee strength and quality of our ingredients.

We will update this post as further research is published, so stay tuned.

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