Journal

Feeling Stressed?

Fight or Flight Response

Stress Busters!

When we are stressed our body releases a hormone called cortisol. If your cortisol levels remain high for prolonged periods, it can cause weight gain, high blood pressure, and even diabetes.

Saffrosun helps lower cortisol levels and regulate our 'happy hormone', serotonin. Made from clinically proven saffron, Saffrosun Calm creates a sense of calm, reduces anxiety, lifts the mood, and improves sleep quality.

What is blood pressure?

Blood pressure is made up of 2 numbers. The top number is called the systolic blood pressure and measures the pressure your heart is under when blood is pumped out around the body. The bottom number is called the diastolic blood pressure and measures the pressure in our vessels between heartbeats. Blood pressure is measured in millimetres of mercury (mmHg). You may also have heard of high blood pressure referred to as hypertension. In general, women have lower blood pressure than men, this difference decreases as women enter the menopause.

Blood pressure differs depending on your age and this can be seen below:

Blood pressure ranges for adults – 16yrs+

Low BP is classed as under 90/60 mmHg

Ideal BP – Between 90/60 mmHg and 120/80 mmHg

Pre-high blood pressure – Between 120/80 mmHg and 140/90 mmHg

High BP - Over 140/90 mmHg. For over 80-year-olds, this would be 150/90 mmHg 

Source: Blood Pressure UK

How can I check my blood pressure?

There are many ways you can check your blood pressure. You can go to your local pharmacy for a free blood pressure check, call your GP surgery or take it yourself at home with a blood pressure monitor. Blood pressure monitors can be bought from pharmacies, big retailers and online.

If you do decide to take your own blood pressure at home here are a few tips to try and prevent an inaccurate reading:

• Drinking caffeine or smoking should be stopped 30 minutes prior
• Give yourself 5 minutes of quiet time before attempting to take the reading
• Take your blood pressure seated with your legs uncrossed and flat on the floor
• Place the blood pressure cuff around your bare arm and make sure the wire is facing upwards and in a central position.
• Place your arm in a relaxed bent position, preferably resting on a table or the arm of a chair
• Don’t talk whilst your blood pressure is being taken
• Press the start button
• Document the reading. Such as 120/80
• Do this 3 times with a 1–2-minute pause in between

If you are trying to track and compare your blood pressure it is recommended to take your blood pressure at the same time each day.

When getting your blood pressure done at the pharmacy or GP surgery most of the above will be done for you but you may find that the reading is higher than when you take it yourself at home. This could be due to something called “white coat syndrome” which is when just being in a healthcare setting increases blood pressure due to anxiety, stress or worry. GPs may offer you a portable 24-hour blood pressure monitor to take home. The monitor measures your blood pressure at regular intervals throughout the day whilst doing your day-to-day activities.

Try taking your blood pressure in both arms and seeing if there is a difference.  A small difference in blood pressure readings (around 10 mmHg) between each arm is normal. However, a difference of more than 10 mmHg might be a sign to talk to your doctor. The difference can be in the top number or the bottom number. This could be a sign of peripheral artery disease or developing heart disease in future.

When is the best time to take blood pressure?

The best time to take your blood pressure is twice a day, in the morning and in the evening to get an overall view of how your blood pressure is doing throughout the day.

In the morning, our blood pressure is at its lowest and in the evening between 4 pm and 6 pm, it is at its highest. Our blood pressure can fluctuate by up to 30% throughout the day due to our hormones, our activity level and eating habits.

Ultimately, the best time to take your blood pressure is when it suits you and your lifestyle.

What causes high blood pressure?

There are many causes for high blood pressure. These can be singular or additive or because of a health condition:

• Sedentary lifestyle
• Poor diet
• High stress levels
• Age – Over 50 years old
• Smoking
• Overconsumption of alcohol
• Overweight
• Lack of physical activity
• High salt intake
• Family history of high blood pressure especially in black and Asian populations

High blood pressure can also be caused by other health conditions such as:

• Diabetes
• Kidney problems
• Sleep apnoea
• Thyroid problems 

Signs of high blood pressure

High blood pressure doesn’t often result in symptoms until blood pressure is at extremely high levels. You may not realise we have high blood pressure and feel completely normal which is why we should be checking it more frequently as we age. However, there are some physical signs and symptoms that could occur to look out for:

• Visual disturbance – blurred vision, floaters
• Headaches
• Shortness of breath
• Nosebleeds

Blood pressure during the menopause and pregnancy

Hormonal changes such as menopause can indirectly result in higher blood pressure because oestrogen drops during menopause. This female hormone plays a vital role in protecting our cardiovascular system. It stimulates our blood vessels to relax and widen allowing blood to flow more easily. Oestrogen dropping during the menopause has been linked to an increased risk of cardiovascular disease therefore keeping an eye on our blood pressure is recommended.

Blood pressure during pregnancy normally decreases in the first and second trimesters, however high blood pressure can occur and result in the following:

Chronic hypertension

This is high blood pressure before 20 weeks gestation — a woman with high blood pressure before week 20 of pregnancy is likely to have pre-existing high blood pressure.

Gestational hypertension

This is high blood pressure that is new and occurs after 20 weeks' gestation and there is no protein found in the urine.

Pre-eclampsia

This is new high blood pressure presenting after 20 weeks gestation with significant protein from in urine. Pre-eclampsia is a multi-system disorder which can affect the organs of the mother. It is a concern and seeking medical advice immediately is needed. Some of the physical symptoms of pre-eclampsia include vision disturbances, severe headaches, sudden swelling of the face, hands/feet, vomiting and breathlessness.

What causes low blood pressure?

Movements such as going from lying to standing up can sometimes make us feel lightheaded or dizzy for a brief period of time. This is due to something called postural hypotension. This can occur when you are dehydrated due to lower blood volume.  

Medications that are taken to lower blood pressure may be taken incorrectly or too much taken can result in low blood pressure.  This can also happen with water tablets (diuretics) and heart disease.

Low blood pressure can sometimes also be a sign of a life-threatening emergency such as sepsis, an allergic reaction (anaphylaxis) or heavy blood loss.

What are low blood pressure symptoms?

Low Blood pressure is below 90/60 mmHg and may be accompanied by some of the symptoms below:

• Dizziness
• Lightheaded
• Fainting
• Tiredness
• Confusion
• Falling

How to reduce high blood pressure?

Blood pressure tablets to treat high blood pressure may be prescribed to you. These blood pressure medications are split into various categories and have different mechanisms of action. Below are some of the main groups of medication for high blood pressure.

• Angiotensin converting Enzyme (ACE) inhibitors such as ramipril. Common side effects include a dry cough, dizziness and headaches
• Calcium Channel blockers such as amlodipine. Common side effects include ankle swelling, constipation and headaches
• Angiotensin receptor blockers (ARB) such as candesartan. Common side effects include headaches, dizziness
• Diuretics such as Bendroflumethiazide. Common side effects include needing to go to the bathroom more frequently, postural hypotension and increased thirst.

The timing of your blood pressure medication is down to personal preference if taking a once-a-day dosage. It might be a clever idea to take blood pressure medication at night to minimise the risk of falls and dizziness. However, this wouldn’t be a good idea if taking diuretics due to the side effects of urinary frequency; these would be best taken in the morning.

Statins are also another group of medications that can indirectly lower your blood pressure by reducing cholesterol especially low-density lipoproteins (LDL). Too much of this type of cholesterol can build up along the artery walls and create a narrowing of the arteries resulting in an increase in blood pressure

How to lower blood pressure naturally

We offer a few natural alternatives that could help reduce blood pressure and can be used alongside blood pressure medications and other prescribed medication such as statins:

• Black Garlic
• Marine Magnesium
• Metabolic Gold

These three supplements can be taken together and work in different ways.

Black Garlic with Vitamin D

Our Black Garlic contains fermented black garlic which is more potent than normal raw garlic. Normal garlic contains Allicin and during the fermentation process, Allicin converts to S-Allyl Cysteine (SAC) which is the natural compound responsible for stimulating circulation and lowering blood pressure. Black Garlic can help blood flow more easily and this is why we wouldn’t recommend taking it if you are on any blood thinners or antiplatelets such as Warfarin, Apixaban, Clopidogrel and Aspirin.

Metabolic Gold

Our Metabolic Gold contains Bergamot fruit extract and Artichoke Leaf extract. Both ingredients may improve certain risk factors for heart disease. Lowering cholesterol levels to avoid atherosclerosis and build up along the vessel walls which narrows them resulting in increased blood pressure.

Marine Magnesium

Our Marine Magnesium can also help with blood pressure by relaxing the blood vessels.

Nutrition

Other than supplements we can help our blood pressure through the food we eat and don’t eat.

• Reduce salt intake to less than 6g per day – Not all salts are the same. Here we are referring to table salt that contains sodium.
• Increase consumption of healthy unsaturated fats - oily fish, avocado, eggs and nuts/seeds.
• Reduce consumption of artificial sugars and saturated fats.
• Reduce alcohol intake – 14 units weekly. Try to spread them over a few days rather than consuming them all at once as our liver finds it hard to process. What does a unit of alcohol look like? 40% spirit (25ml), wine (100ml), Beer (180ml).

Exercise

The main thing when it comes to exercise is to do something you enjoy and that you can be consistent with. For heart health, we need to do some form of cardiovascular exercise such as walking, running, swimming or cycling.

150 minutes of moderate intensity (you can still hold a conversation) cardio or 75 minutes of vigorous intensity (you can only speak a few words) cardio a week is recommended by the NHS. It has now been shown that muscle mass and cardio-respiratory fitness are linked with longevity. A full body strength training session is an effective way to do this, aiming for twice a week to maintain muscle mass especially as we age.

Speak to our expert pharmacists today

A key element of our vision is accessibility to our expert advice service; allowing customers to make a personalised and considered decision when it comes to their health. 

Our pharmacists are on hand Monday – Friday 9 am – 5 pm. Book your free consultation today! Book Now!

Charlotte Parker-Lennox

Charlotte is a pharmacist with 6 years of experience working in retail pharmacy and integrated urgent care (IUC) alongside nurses, paramedics and doctors.

She has changed the direction of her career to support people with a holistic approach to wellness by treating the root cause of your health concerns. She enjoys an outdoor challenge, completing marathons and cycling adventures around the UK.

Many of us have experienced moments where our mind feels clouded, making concentration and memory recall more challenging than usual. This is commonly referred to as brain fog and can be very frustrating to deal with. While it’s not a medical diagnosis in itself, brain fog is a symptom that can significantly impact your quality of life.

What is brain fog?

Severe brain fog can be debilitating, particularly if you need to function day-to-day in a high-performance or pressured environment at home or work. It can affect your levels of confidence, self-esteem and performance.

Brain fog causes

Many factors can contribute to brain fog such:

Lifestyle Factors: Poor sleep quality, lack of exercise, and a nutrient deficient diet.

Medical Conditions: Chronic fatigue syndrome, fibromyalgia, anaemia, depression, thyroid disorders. diabetes and post viral syndrome are among the conditions associated with brain fog.

Medications: Certain medications can affect cognitive function as a side effect.

Stress and Mental Health: High-stress levels and mental health issues like anxiety and depression are closely linked to brain fog.

Other factors that can affect brain fog are age, hormonal changes, nutritional deficiencies, and even the aftermath of conditions such as COVID.

Brain fog symptoms

Brain fog manifests as cognitive impairments including:

• Mood swings
• Lack of focus
• Irritability
• Confusion
• Trouble sleeping,
• Low energy or fatigue
• Forgetfulness
• Trouble concentrating
• Low motivation
• Difficulty making decisions

Menopause brain fog

Brain fog during perimenopause and menopause is a real and sometimes challenging symptom faced by many going through the hormonal transition. 

Hormonal fluctuations - particularly a decrease in oestrogen and testosterone - are believed to play a critical role in this. When the levels of these hormones begin to fall during perimenopause and menopause, you can experience a range of cognitive symptoms including memory loss, difficulty staying focused, losing your train of thought, and getting confused easily.

Oestrogen is involved in regulating neurotransmitters that affect cognition, including serotonin and dopamine. As these hormone levels fluctuate, so does the clarity of thought, making brain fog a frequent complaint amongst menopausal women.

Testosterone strengthens nerves in the brain and contributes to mental sharpness and clarity, as well as overall energy levels. It also strengthens arteries that supply blood flow to the brain, which is crucial to protect against loss of memory.

Brain fog is very common. In research conducted by the British Menopause Society, almost 40% of the women interviewed reported issues with memory and concentration as they go through the menopause.* 

*Menopause - Understanding the impact on women and their partners.

The COVID connection

Post-COVID brain fog has emerged as a lingering symptom for many individuals recovering from the virus due to consequences such as inflammation and the overall stress of dealing with the illness. 

In one study, 7.2% of people who reported having long COVID experienced brain fog, and this symptom was more common in those who had a more severe case of COVID-19. 

Stress

Chronic stress can increase blood pressure, weaken the immune system, and trigger depression. According to a study undertaken in 2017, stress can also cause mental fatigue.

Chronic stress leads to sustained high levels of cortisol, the body's stress hormone. High cortisol levels can impair cognitive function such as memory and concentration, contributing to brain fog.

Stress can also disrupt the balance of neurotransmitters, such as serotonin and dopamine, which play crucial roles in mood regulation, focus, and cognitive processing. Imbalances in these chemicals can lead to difficulties in concentrating and memory lapses.

Chronic stress is linked to increased inflammation in the body, which can negatively affect brain function and lead to symptoms of brain fog.

Medications

Brain fog is a known side effect of certain medications, such as certain painkillers, antidepressants and sleep medications.

Brain fog can also occur after cancer treatments. This is often referred to as ‘chemo brain’.

Sleep

The NHS recommends that adults should aim for 7 – 9 hours of sleep each night. However, Nuffield Health surveyed 8,000 adults in the UK and found that most adults are getting an average of 5.9 hours of sleep every night in 2023.

Poor sleep quality and sleep deprivation can significantly contribute to cognitive impairments, including reduced attention span, memory issues, and decreased mental clarity.

How to clear the fog

Brain fog can be frustrating, but relief is possible. You should not ignore your symptoms because, if left untreated, brain fog can impact your ability to function and undertake tasks.

Addressing brain fog involves treating underlying causes or making lifestyle changes to improve cognitive function, these include:

Sleep: Ensuring adequate, high-quality sleep can significantly reduce symptoms of brain fog. Aim for 7-9 hours per night and maintain a consistent sleep schedule.

Nutrition: A diet rich in fruits, vegetables, whole grains, and omega-3 fatty acids (found in fish) can support brain health. Avoiding excessive alcohol, sugar, and processed foods is also advisable.

Exercise: Regular exercise increases blood flow to the brain and has been linked to improved cognitive function. Activities like walking, swimming, and yoga can be particularly beneficial.

Stress Management: Techniques such as mindfulness, meditation, and yoga can reduce stress and improve mental clarity.

Hydration: Adequate hydration is crucial for maintaining cognitive function. Aim for 8 glasses of water daily.

Mental Stimulation: Engage in activities that challenge your brain, such as puzzles, learning a new skill, or reading.

Magnesium  

Magnesium is an essential nutrient that plays a pivotal role in over 300 physiological processes in the body, including those involved in energy production, sleep quality, and the regulation of neurotransmitters. It’s, therefore, no wonder that magnesium has been identified for its potential to alleviate brain fog.

Magnesium aids in improving brain function by supporting the nervous system, enhancing sleep quality, reducing inflammation, and reducing stress levels—all factors that can mitigate the symptoms of brain fog. For those individuals navigating menopause, magnesium's role in balancing hormones further highlights its significance.

Marine magnesium supplements

Marine Magnesium can help to restore clarity for anyone experiencing brain fog. Our bodies require this micromineral to function healthily however our bodies do not synthesise or store magnesium. It is therefore essential that we get an adequate daily intake from our diet or high-quality food supplements. 

“There are so many magnesium supplements on the market, which one should I choose?”

We understand how overwhelming it can be when deciding on which Magnesium supplement you should be taking. The key to selecting the most suitable supplement lies in understanding the difference in the quality and purity of the different supplements available.

Our Marine Magnesium is sourced from purified seawater and is in the form of magnesium hydroxide. Due to its natural and pure source, it is quickly absorbed by the body making it more effective and very gentle on the stomach. 

Marine Magnesium contains only 3 ingredients:

1. Magnesium (from seawater)
2. Organic baobab (natural prebiotic) 
3. A natural, tapioca capsule shell. 

Most other magnesium supplements such as magnesium glycinate, citrate, picolinate and taurate are synthetic and manufactured using chemicals and often contain numerous additives, fillers and bulking agents. 

Like your food, it is best to avoid supplements that are overprocessed and contain unnecessary additives that can often affect the supplement's effectiveness and even be harmful to health. Remember to always read ingredient labels to help you choose your supplements wisely - choose NAKED.

Best magnesium supplement

Marine Magnesium has been voted as one of the best magnesium supplements by experts in The Independent. Maz Packham, a nutritionist says:

Best magnesium supplements, approved by experts | The Independent

Shop Marine Magnesium now

Call our Pharmacists if you have concerns

If you have any concerns about brain fog or any other health conditions, please call our pharmacists for free advice. (+44) 01483 685 630

Dimple Varu

Dimple is a pharmacist with 12 years of experience working in retail and general practice and now specialises in providing education and advice on natural supplements.

She believes in the power of nature and using natural existing compounds to enhance our health, whether that’s treating pain or helping to prevent long-term conditions. Mum of 1, living a busy life, loves reading and baking if she has the time.

We are all guilty of over indulging at certain times of year, over eating, drinking too much or consuming too much sugar.

However, as you get older you may find that it is taking longer to bounce back and you may become intolerant to certain types of foods and alcohol.

If you suffer from headaches and migraines you may be reaching for painkillers such as Ibuprofen which, although an effective anti-inflammatory, has long term side effects including increasing cardiovascular risks and damaging the protective lining of the gut. Ibuprofen is only effective for up to 6 hours, so you may need to take repeated doses!

Did you know that Turmeric with the correct range and strength of 7 curcuminoids, has multiple anti-inflammatory benefits, works just as well as Ibuprofen or aspirin and actually improves gut health.

Scientific research (ref see below) has demonstrated that curcuminoinds, the active compounds in turmeric, are effective at removing both the cause and symptoms of a hangover.

Curcuminoids are potent antioxidants. Alcohol consumption can cause oxidative stress that damages your cells, so an effective antioxidant is vital before, during and after a heavy night.

So the perfect natural solution for hangovers should be taken before you go out and again when you wake up:

Natruflex Turmeric: We recommend that you take Natruflex Turmeric 1-2 capsules BEFORE you go out and when required during the next day. 

Gut Love: Containing, 21 probiotics and 2 organic prebiotics. take 1 capsule daily to settle the digestion and improve the excretion of toxins for a minimum of 14 days.

Marine Magnesium: Take 1 capsule at night to restore healthy nerve and muscle function for a minimum of 7 days.

Vitamin D3: Take 2 capsule daily for at least 30 days

How can Metabolic Gold help?

Metabolic Gold contains Bergamot fruit extract and Artichoke leaf extract. It is the perfect blend of naturally sourced, high strength ingredients that work together synergistically to help reduce sugar levels, improve insulin resistance, balance cholesterol, reduce fat around the waistline and reduce fatty liver.

In a recent trial of 60 patients who were overweight and had high cholesterol, subjects were treated with a combination of bergamot extract and artichoke leaf extract for 2 months and compared to a group that received a placebo for the same amount of time. The results showed a significant decrease in total and LDL cholesterol as well as a significant reduction in waist circumference.

When combined with lifestyle efforts focusing on diet, exercise, sleep and stress, the combination of bergamot fruit and artichoke leaf extracts can provide significant health benefits.

We recommend this supplement is taken for at least 3-4 months at a dose of one capsule twice a day with or after food.

PUBLISHED RESEARCH:

Dinkova-Kostova A. Relation of structure of curcumin analogs to their potencies as inducers of Phase 2 detoxification enzymes. Carcinogenesis. 1999;20(5):911-914.

https://pubmed.ncbi.nlm.nih.gov/35070194/

https://pubmed.ncbi.nlm.nih.gov/35668500/

https://pubmed.ncbi.nlm.nih.gov/30395947/

https://pubmed.ncbi.nlm.nih.gov/36370961/

Whether you are a novice or competitive athlete, when you undertake any exercise, you want to take preventative measures to reduce muscle damage.  

During exercise the two leading causes of muscle damage are inflammation and oxidative stress.

The natural bioactive polyphenols of the spice turmeric called curcuminoids have been shown to counteract both inflammation and oxidative stress caused by exercise.

Exercise-induced muscle damage (EIMD) leads to the onset of an inflammatory response that is associated with a decrease in the ability to generate muscle strength, decreased range of motion, localised swelling, delayed onset muscle soreness and increased muscle proteins in the blood (such as creatine kinase, lactate dehydrogenase and myoglobin).

Inflammatory responses are always linked to oxidative stress and both are directly involved in EIMD.

The Science Bit

A 2020 review showed that supplementing with turmeric extract at a dose between 150mg – 1500mg per day before and during exercise and up to 72 hrs post exercise improved performance by reducing exercise-induced muscle damage and reducing inflammation caused by physical activity. Read PubMed Article 

Another review showed that participants who supplemented with a turmeric extract demonstrated reduced inflammation and oxidative stress, decreased pain and muscle damage, superior recovery and muscle performance and improved gastrointestinal function. The review concluded that curcumin supplementation appears to be safe and beneficial for sport and exercise in humans. Read Review

Natruflex Turmeric 

Our supplement Natruflex Turmeric contains 800mg turmeric extract (curcuminoids) per 2 capsules.

It is combined with black pepper for better absorption and naturally sourced marine magnesium, which further supports nerve function.

Taking curcumin is much gentler on the body than taking non steroidal anti-inflammatory medication, which can cause adverse effects such as heartburn and stomach ulcers.

If you’re looking to further enhance your stamina and exercise performance:

• Try adding 1-2 tablespoons of chia seeds to your daily diet. These tiny seeds are super packed with protein, omega 3 and omega 6 oils, calcium, iron, zinc and rich in antioxidants. When mixed with water and allowed to soak, these seeds release a form of gelled water that hydrates more slowly and effectively than just drinking liquid alone.

The Aztecs so treasured chia that they used to gift it to their king in homage and Aztec runners used to chew on the seeds as they went into battle. 

Chris McDougall’s book “Born to Run” describes how the Tarahumara Indians of Mexico’s Copper Canyons – known to be ultra-runners, running hundreds of miles without rest and enjoying every mile of it, fuelled themselves with a beverage containing chia seeds called ‘Iskiate’ and you can add a Natruflex Turmeric opened capsule an you have the perfect natural drink for recovery and fuel.