Journal
Metabolic Gold for Liver Health
"It's estimated that up to 1 in every 3 people in the UK has early stages of Non Alcoholic Fatty Liver Disease"
SOURCE: NHSINFORM
When our fat cells can’t cope anymore with storing fat – the liver takes the burden and becomes the “overflow” storage organ for fat. This sets the stage for a vicious cycle and metabolic dysfunction.
As the fats in blood increase, gene function in the liver is inhibited causing more fat to be dumped there. At the same time, levels of leptin are increased – causing a corresponding fall in the fat-burning hormone known as adiponectin. Low adiponectin levels lead to insulin resistance in the liver – which then causes blood sugar to rise – and this sugar is then converted to more fat.
Early symptoms of NAFLD (Non Fatty Liver Disease) may be mild:
- Extreme Fatigue
- Discomfort in upper right abdomen
- Difficulty losing weight
- Weakness
Losing weight can help to slowly unclog the liver, reduce the amount of stored fat, thereby speeding up the metabolism as well as to help to reduce blood sugar, harmful LDL cholesterol and triglycerides.

Dietary suggestions to unclog the liver and support its optimal function:
- A Mediterranean diet (vegetables, fruits, antioxidant spices and herbs, whole grains, oily fish, nuts and olive oil) have been shown to benefit liver health.
Liver nourishing foods include : cruciferous veg (Brussels sprouts, cauliflower, kale, cabbage, broccoli, rocket (arugula), watercress)
Bitter foods: rocket, radicchio, dandelion greens
- Practising some intermittent fasting can also help un-clog the liver, even if you can only manage a 12 hour overnight fast, as it allows the body to rest and regenerate.
- Ensure you are eating enough protein. If you are not consuming enough protein this can impair your liver’s ability to carry out it’s detoxifying and metabolic functions.
- Drink plenty of pure water to help flush out excess toxins.



The great news is that we can support our hard working liver with specific nutrients which have been supported by scientific research:
- AGED GARLIC can help shift unwanted fat from being dumped in the liver.
- VITAMIN D deficiencies are linked to NAFLD (Non Alcohol Fatty Liver Disease) : Vitamin D deficiency leads to the release of pro-inflammatory agents that can contribute to fatty liver disease
- BERGAMOT & ARTICHOKE EXTRACTS - Bergamot fruit extract has been shown to lower blood sugar, reduce inflammation, improve blood vessel activity and artichoke boosts your production of bile.




Metabolic Gold for Insulin Resistance
Insulin resistance causes fat storage
Insulin is known as “the fat storer” hormone and is strongly influenced by carbohydrate intake and overconsumption of food, causing a detrimental increase in your blood sugar.
When insulin resistance occurs, sugar can’t get into your cells the way it normally would and the result is that this sugar gets stored as fat.
How can you reduce insulin resistance?
- Diet (Mediterranean diet, intermittent fasting)
- Increased physical activity such as HIT
- Supplement regularly with Metabolic Gold
How can Metabolic Gold help with insulin resistance?

Metabolic Gold is a unique, safe and effective natural supplement that contains the highest strength bergamot fruit extract and artichoke leaf extract to improve sugar metabolism, balance blood sugar and reduce insulin resistance.

Metabolic Gold
Poor metabolic health affects one in four UK adults in the UK and is the leading cause of an increased risk of heart disease, stroke and type 2 diabetes.
The risk factors for poor metabolic health are:
- high sugar levels
- Insulin resistance
- abnormal cholesterol levels
- excess fat around the waistline
- fatty liver
- elevated blood pressure
Symptoms
Most of the conditions associated with metabolic health don't have obvious signs or symptoms and require a blood test to determine (such as cholesterol levels). However, a large waist circumference is something that you would visibly notice and if your sugar levels are high, you might notice the signs and symptoms of diabetes — such as increased thirst and urination, fatigue, and blurred vision.
Preventing or reversing poor metabolic health
The risk factors listed above are all modifiable with adopting a healthy lifestyle which should include:
- Eating a healthy, balanced diet consisting of fruits and vegetables, whole grains (brown rice), proteins (pulses such as lentil) and avoiding over processed and refined foods such as microwave meals and sugary treats is key.
- Exercising regularly. Undertaking a minimum of 30 mins of physical activity a day 5 days a week.
- Cutting back on alcohol and smoking can be a really effective way to improve your metabolic health, boost your energy, lose weight and save money.
How can Metabolic Gold help?
Metabolic Gold contains Bergamot fruit extract and Artichoke leaf extract. It is the perfect blend of naturally sourced, high strength ingredients that work together synergistically to help reduce sugar levels, improve insulin resistance, balance cholesterol, reduce fat around the waistline and improve fatty liver.
In a recent trial of 60 patients who were overweight and had high cholesterol, subjects were treated with a combination of bergamot extract and artichoke leaf extract for 2 months and compared to a group that received a placebo for the same amount of time. The results showed a significant decrease in total and LDL cholesterol as well as a significant reduction in waist circumference.
When combined with lifestyle efforts focusing on diet, exercise, sleep and stress, the combination of bergamot fruit and artichoke leaf extracts can provide significant health benefits.
We recommend this supplement is taken for at least 3-4 months at a dose of one capsule twice a day after food
Metabolic Gold for Managing Weight and Sugar Naturally
Introducing our new formula containing pharmaceutical strength bergamot and artichoke extracts. Metabolic Gold has been over two years in research and developement.
Bergamot may sound familiar as the peel of this unique citrus fruit is used for teas, perfumes and essential oils.
However, we only utilise the fruit sourced from trees found in the coastal areas of Calabria, Southern Italy as it's unique combination of five polyphenol bioactives reduce the levels of unhealthy fats in a similar manner to statin medications, without the side effects.
Bergamot fruit polyphenols have been scientifically proven to improve levels of good cholesterol, reduce inflammation and improve blood vessel elasticity.

Bergamot fruit extract
Bergamot polyphenols improve the way fats are processed in the liver thereby balancing cholesterol and protecting cardiovascular health.

Artichoke leaf extract
It boosts your liver’s production of bile. Bile is a natural compound that digests and uses fats so they don’t accumulate in your liver or in your body.
How do you take Metabolic Gold?
A randomized placebo-controlled study with 60 overweight adults showed that supplementing with 600mg bergamot and 100mg artichoke leaf resulted in a reduction in LDL cholesterol, significant reduction in waist circumference and visceral adipose tissue in 2 months – even in participants who did not follow a low-calorie diet.

Concerned about side effects?
The natural formulation of Metabolic Gold means that you can take it alongside most medications, however we recommend that you take a few minutes to call us, or write to us and get some friendly pharmacist advice if you have any questions about your current regime.
"Metabolic Gold is effective because of the botanical sources, strength of the bioactives, scientific research and pharmaceutical quality of the formulation. The unique combination of the artichoke plus bergamot extracts will help so many people who have a sluggish metabolism, fatty liver alongside problems of sugar and cholesterol balance."

Why do I need a broad-spectrum probiotic?
When gut health is good, you’ll feel balanced – when it’s off, you may experience a variety of symptoms and this imbalance can also affect your emotional health, your immune system and skin health.
Signs you could benefit from taking a probiotic?
- You’ve taken a course of antibiotics
- You eat a lot of refined sugar
- You’ve taken a course of antacid medfication
- You experience bloating
- You have a lot of gas
- You suffer from loose stools/diarrhoea
- You regularly get constipated
- You have skin issues triggered by certain foods
50% of our stools are actually bacteria that have been living in your gut – therefore these bacteria need replacing everyday.
So how can we replace these wonderful hard working bugs?
- Plant-based fibre - helps our gut bugs thrive aim for ideally around 30g per day, ensuring vegetables and fruits of all the colours of the rainbow are included in a week.
- Fermented foods can boost the number of friendly bacteria in your gut, Kefir, sauerkraut, kimchi, miso, kombucha, pickles (in salty brine), tempeh, natto, unsweetened yoghurt
- Prebiotics : these are like fertiliser for our new and current gut flora and include:
- Baobab fruit
- Moringa leaf
- Chicory root
- Dandelion greens
- Jerusalem artichoke
- Garlic, Onions, Leeks
- Asparagus
- Bananas
- Barley, Oats
- Apples (with the skins)
- Dark chocolate
- Flaxseeds (also known as linseeds)
- Potatoes/pasta that have been cooked the day before and left in the fridge overnight
Why taking a probiotic could help?
Our GUT LOVE is a great multi-strain probiotic that can be taken daily, containing 19 different strains of live bacteria to help replenish your gut flora with a variety of strains.


Body shape is not an indicator of the strength of your blood vessels
Did you know that the blood vessels in your body are nearly 60,000 miles long which is twice around the world.
Their job is to carry vital blood, oxygen and essential nutrients to every part of the body. Healthy vessels are strong, elastic, flexible and clear of any deposits.

What causes a stroke?

So what can we do to keep our blood vessels unclogged, strong and healthy?
- Follow - the principles of a Mediterranean-style diet rich in a variety of fresh fruit and vegetables, ideally 6 portions a day and include a daily portion of a vegetable rich in nitric oxide, such as beetroot, broccoli, spinach, collard greens and kale. Nitric oxide is a substance that is essential for optimal arterial health and function. Eat regularly.
- Move - Aim for 30 minutes 5 times a week. However, research is growing that 'snack size' consistent exercise is just as impactful on our bodies and our mind. Dr Chatterjee is a huge advocate for adding an exercise snack with your daily routine so add squats as the kettle is boiling, or toe raises whilst brushing your teeth 5 minutes a day is better than nothing and consistency is key.
- Stop - smoking.
- Maintain - low LDL cholesterol by reducing your consumption of processed and deep-fried foods.
- Lose - weight carrying extra weight increases your chances of having too much LDL cholesterol in your blood, leading to fatty deposits building up in the arteries, restricting blood flow. Studies show that even losing 5% of your body weight can improve cholesterol levels.
Our Metabolic Gold, is made from Bergamot (Citrus Bergamia) only grown in Calabria in Italy and can be used to support the health of your arteries by reducing cholesterol and supporting weight management.
Studies show that bioactive compounds in Bergamot can reduce the “bad” fats, lowering LDL cholesterol, triglycerides and improving total cholesterol levels.
In fact, Research on Bergamot has been shown to have 2 specific molecules that are very similar in structure, and function to statins.
Metabolic Gold can generally be used in conjunction with prescribed cholesterol-lowering medication – speak to one of our pharmacists for more information about your health and any potential indications with current medication

How to avoid the two main deficiencies in a vegan diet?
The number of vegans has been growing rapidly over recent years and the concept of vegetarianism is not new dating back as early as 500 BC, first mentioned by Pythagoras.
In Great Britain, the number of vegans is estimated to have quadrupled between 2014 and 2019.
Famous vegans
Novak Djokovic, Venus and Serena Williams, Lewis Hamilton, Mike Tyson, Martina Navratilova, David Haye are great examples that veganism offers one the potential to not only be healthy, but also for elite athletes to thrive.
Some key nutrients vegans should be aware of
Although there are health benefits to a vegan lifestyle, it is also important to recognise that, as with any diet, if not appropriately planned then it is easy to become nutritionally deficient as there are certain nutrients that are not available from plants.
Below are some of the 2 key nutrients that vegans need to be aware of to avoid deficiencies or imbalances.
Vitamin B12
Vitamin B12 is an essential nutrient, which does not originate in plants, but from bacteria.
In fact, B12 supplements are (for the most part) also given to farm animals, meaning even those on non-vegan diets are supplementing, but indirectly.
Symptoms of B12 deficiency may include:
- A pale yellow tinge to your skin
- A sore and red tongue (glossitis)
- Mouth ulcers
- Pins and needles (paraesthesia)
- Disturbed vision
- Irritability
- Unexplained sadness
- A decline in your mental abilities, such as memory, understanding and judgement
Due to B12 not being readily present in a vegan diet it’s recommended to supplement this, especially for strict vegans.
Two tablets daily of our Saffrosun Calm offers 100% of the Nutritional Reference Value (NRV).
Vitamin D
Vitamin D is the “sunshine vitamin”, and although it is possible to obtain this through certain plant foods such as mushrooms, in general it is not broadly consumed on a vegan diet.
In fact, the NHS advises that "everyone (including pregnant and breastfeeding women) should consider taking a daily supplement containing 10 micrograms of vitamin D during the autumn and winter” [Source [9]].
Symptoms of Vitamin D deficiency may include:
- Fatigue
- Not sleeping well
- Bone pain or achiness
- Feelings of sadness
- Hair loss
- Muscle weakness
- Loss of appetite
- Getting sick more easily
Again, it is good practice to use a supplement to ensure you are getting the recommend intake of Vitamin D, particularly in colder seasons with having less sun exposure. One capsule of our Pure Organic Vitamin D offers 200% of the NRV, and one capsule of our Vitamin D3 contains 100% NRV.
Probiotics
Probiotics promote a healthy balance of gut bacteria, and studies suggest that taking probiotics are linked to a range of health benefits. These include benefits for gut function, immune function, respiratory tract infections, and duration of illness.
Although vegans generally consume a diet rich in fibre, which is a key gut nutrient and it is possible to acquire probiotics from plant-based sources such as fermented foods (e.g. sourdough bread and tempeh), vegans don’t consume the most common probiotic rich foods such as yogurt and kefir.
Our Gut Love supplement contains 21 probiotics and prebiotics, and 19 billion good bacteria to support overall gut health including one probiotic which originates from soil.
The Naked Pharmacy Supplements
All of The Naked Pharmacy’s own brand of supplements are entirely vegan and contain natural ingredients, meaning higher absorption and bioavailability than synthetic supplements.